ever heard of carbicarb !!
Unfortunately Carbicarb is not available in USA but available in canada. It is a combination of sodium bicarbonate and sodium carbonate. It has been in use for about 20 years with good track record.
It has advantage over 'soda-bicarb' (NaHCO3) of not undergoing significant breakdown into CO2 and H2O. Also it is more predictable in raising PH. The dose is
0.2 x base deficit = mEq Sodium
Related previous pearl: THAM
Reference: click to get abstract
1. Improved hemodynamic function during hypoxia with Carbicarb, a new agent for the management of acidosis Circulation, Vol 77, 227-233, Copyright © 1988
2. Carbicarb, sodium bicarbonate, and sodium chloride in hypoxic lactic acidosis. Effect on arterial blood gases, lactate concentrations, hemodynamic variables, and myocardial intracellular pH Chest, Vol 104, 913-918, Copyright © 1993
